Yoshihisa Koga Selected Research

N- (4- isopropyl- 2,2- dimethyl- 3- oxo- 3,4- dihydro- 2H- benzo(1,4)oxazine- 6- carbonyl)guanidine

9/2004	[The effects of Na+ -H+ exchange inhibitor, KB-R9032, administered at the time of reperfusion in perfused rat heart].
1/2004	KB-R9032, newly developed Na(+)/H(+) exchange inhibitor, attenuates reperfusion-induced arrhythmias in isolated perfused rat heart.

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Yoshihisa Koga Research Topics

Disease

5	Pain (Aches) 03/2014 - 06/2002
2	Hyperalgesia 08/2012 - 02/2011
2	Neoplasms (Cancer) 02/2010 - 04/2002
2	Ventricular Fibrillation 12/2009 - 01/2004
2	Stroke (Strokes) 02/2007 - 03/2006
2	Hypertension (High Blood Pressure) 02/2007 - 03/2006
2	Cardiac Arrhythmias (Arrythmia) 09/2004 - 01/2004
2	Ischemia 09/2004 - 01/2004
1	Bipolar Disorder (Manic Depressive Psychosis) 01/2020
1	Arthritis (Polyarthritis) 01/2019
1	Hyperthermia 08/2012
1	Inflammation (Inflammations) 02/2011
1	Paralysis (Palsy) 04/2010
1	Acoustic Neuroma (Acoustic Neurinoma) 04/2010
1	Dyspnea (Shortness of Breath) 04/2010
1	Myocardial Infarction 12/2009
1	Hypersensitivity (Allergy) 10/2009
1	Hypoxia (Hypoxemia) 01/2009
1	Pulmonary Atelectasis 01/2009
1	Neurologic Manifestations (Neurological Manifestations) 01/2009
1	Paresthesia (Dysesthesia) 01/2009
1	Spinal Cord Injuries (Spinal Cord Injury) 01/2009
1	Pleural Effusion (Pleural Effusions) 01/2006
1	Pneumothorax 01/2006
1	Funnel Chest (Pectus Excavatum) 01/2006
1	Postoperative Pain 01/2006
1	Subcutaneous Emphysema 07/2004
1	Stomach Neoplasms (Stomach Cancer) 07/2004
1	Vascular System Injuries 04/2002

Drug/Important Bio-Agent (IBA)

2	Anesthetics (Anesthetic Agents)IBA 03/2014 - 01/2006
2	Carbamazepine (Tegretol)FDA LinkGeneric 02/2011 - 01/2009
2	Local AnestheticsIBA 01/2009 - 01/2006
2	N- (4- isopropyl- 2,2- dimethyl- 3- oxo- 3,4- dihydro- 2H- benzo(1,4)oxazine- 6- carbonyl)guanidineIBA 09/2004 - 01/2004
1	CollagenIBA 01/2019
1	JTE-952IBA 01/2019
1	Capsaicin (Zostrix)FDA Link 08/2012
1	3- (hydroxymethyl)- 4- (5- methylpyridin- 2- yl)- N- (6- (2,2,2- trifluoroethoxy)pyridin- 3- yl)- 3,4- dihydro- 2H- benzo(b)(1,4)oxazine- 8- carboxamideIBA 08/2012
1	CarrageenanIBA 08/2012
1	Voltage-Gated Sodium ChannelsIBA 02/2011
1	Tetrodotoxin (Tetradotoxin)IBA 02/2011
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2009
1	LatexIBA 10/2009
1	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 01/2009
1	Lidocaine (Xylocaine)FDA LinkGeneric 01/2009
1	SteroidsIBA 01/2009
1	Neurotransmitter Agents (Neurotransmitter)IBA 02/2007
1	Taurine FDA Link 02/2007
1	Drinking WaterIBA 02/2007
1	Clonidine (ST 155)FDA LinkGeneric 03/2006
1	ImidazolinesIBA 03/2006
1	Ropivacaine (Naropin)FDA LinkGeneric 01/2006
1	Fentanyl (Sublimaze)FDA LinkGeneric 01/2006
1	Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric 01/2006
1	Sevoflurane (Ultane)FDA LinkGeneric 07/2004
1	Nitrous Oxide (Laughing Gas)IBA 07/2004
1	Blood Coagulation Factors (Coagulation Factor)IBA 04/2002
1	Hemostatics (Antihemorrhagics)IBA 04/2002

Therapy/Procedure

3	Anesthesia 01/2013 - 01/2009
3	General Anesthesia 04/2010 - 07/2004
1	Drug Therapy (Chemotherapy) 01/2020
1	Laryngoscopes 04/2010
1	Electric Countershock (Cardioversion) 12/2009
1	Vascular Surgical Procedures 12/2009
1	Perioperative Period 10/2009
1	One-Lung Ventilation 01/2009
1	Length of Stay 01/2009
1	Catheters 01/2009
1	Ligation 01/2004
1	Artificial Respiration (Mechanical Ventilation) 06/2002
1	Free Tissue Flaps 04/2002
1	Oral Surgery (Maxillofacial Surgery) 04/2002
1	Neck Dissection (Radical Neck Dissection) 04/2002